|Grade Standard||Industrial Grade|
|Molecular Weight||79.1 g/mol|
|Bulk Density||982 Kg/m3|
|Boiling Point||115.2 DegreeC|
|Molecular Weight||122.17 g/mol|
|Boiling Point||162 deg C|
4-Dimethylaminopyridine (DMAP) is a derivative of pyridine with the chemical formula (CH3)2NC5H4N. This colourless solid is of interest because it is more basic than pyridine, owing to the resonance stabilisation from the NMe2 substituent.
Because of its basicity, DMAP is a useful nucleophilic catalyst for a variety of reactions such as esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation, the Steglich rearrangement, Staudinger synthesis of β-lactams and many more. Chiral DMAP analogues are used in kinetic resolution experiments of mainly secondary alcohols and Evans auxiliary type amides.
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